How safe is MP1032? And why is that so important to us?
Our Phase II clinical trial in psoriasis is almost completed. And we are especially interested in one question: Has the good safety profile from our previous studies been confirmed? Nobody wants avoidable side effects. But does it really make sense that we place so much emphasis on a good safety profile in the development of MP1032?
The connection between chronic inflammation and diseases of aging
Is there a
problem with increasing life expectancy? If you look at the graph of average
life years alone, the development over the last fifty years looks very
positive. This graph shows a steady upward trend, especially in Western
countries. People are getting older continuously.
There is, however, a second graph that has risen much slower: that of healthy life expectancy...
MetrioPharm’s lead compound MP1032 entered Phase II clinical testing in early March. How has the study gone so far?
Dr. Petra Schulz: The most important goal of a large Phase II study continues to be to test the safety of the drug, i.e. whether the patients tolerate it well. So far, nobody has had to discontinue the study after taking MP1032, which is a good signal. The other important objectives – proof of efficacy and the search for the optimal dosage – are still unknown, because at the moment the study is blinded.
MetrioPharm presents mode of action of MP1032 at a scientific conference
The 19th Meeting of the Society for Free Radical Research International 2018 in Lisbon
What is the most important step in the development of a new drug? The successful completion of preclinical trials, the first clinical study in humans or the proof of efficacy in patients? All these steps are a precondition for approval; they show that the drug works...
In our last blog entry, our CEO Dr. Wolfgang Brysch replied to the question: “Does MetrioPharm have competition? You can find the full article here. In this article we take a closer look at a drug that has already been tested.
If a patient suffers from an autoimmune disease, for example psoriasis, his physician ...
10 years of MetrioPharm – which one was the most difficult?
Dr. Wolfgang Brysch
Actually, it’s a routine question and I could have expected it. I was asked at our anniversary celebration last fall: “10 years of MetrioPharm – which one was the most difficult?” I had to think about that question for a moment. The year 2007 is not far in the past, still the difficulties of that time feel oddly distant now.
In 2008, right after the founding of the company, we were in...